2,813 research outputs found

    Tank construction for space vehicles Patent

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    Liquid propellant tank design with semitoroidal bulkhea

    Disability Legislation: An Empirical Analysis of Employer Cost

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    As U.S. civil rights legislation, Title I of the Americans with Disabilities Act of 1990 (ADA) was created to eliminate workplace discrimination on the basis of disability. Using the United States as an example, this research analyzes the potential for disability legislation to laden employers with excessive cost burdens, specifically expenses from additional workplace injuries and illnesses. In addition, this study looks at the likelihood that employers compensate for these costs by cutting workplace sick leave benefits. Prior to the ADAā€™s implementation, U.S. employers had the fear of incurring excessive cost. The paper successfully counters this fear by looking first at whether the legislation spawned significant increases in the incident rates of occupational injuries and illnesses, and second, whether employers compensated for soaring compliance costs by decreasing paid sick leave benefits

    Demands and Devotion: Cultural Meanings of Work and Overload Among Women Researchers and Professionals in Science and Technology Industries

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    Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/136323/1/socf12315_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/136323/2/socf12315.pd

    Claytonia virginica L.

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    https://thekeep.eiu.edu/herbarium_specimens_byname/5143/thumbnail.jp

    More than range exposure: global ottersā€™ vulnerability to climate change

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    Climate change impact on species is commonly assessed by predicting speciesā€™ range change, a measure of a speciesā€™ extrinsic exposure. However, this is only one dimension of speciesā€™ vulnerability to climate change. Spatial arrangement of suitable habitats (e.g., fragmentation), their degree of protection or human disturbance, as well as speciesā€™ intrinsic sensitivity, such as climatic tolerances, are often neglected. Here, we consider components of speciesā€™ intrinsic sensitivity to climate change (climatic niche specialization and marginality) together with components of extrinsic exposure (changes in range extent, fragmentation, coverage of protected areas, and human footprint) to develop an integrated vulnerability index to climate change for worldā€™s freshwater otters. As top freshwater predators, otters are among the most vulnerable mammals, with most species being threatened by habitat loss and degradation. All dimensions of climate change exposure were based on present and future predictions of species distributions. Annual mean temperature, mean diurnal temperature range, mean temperature of the wettest quarter, precipitation during the wettest quarter, and precipitation seasonality prove the most important variables for otters. All species are vulnerable to climate change, with global vulnerability index ranging from -0,19 for Lontra longicaudis to -36,9 for Aonyx congicus. However, we found that, for a given species, climate change can have both positive and negative effects on different components of extrinsic exposure, and that measures of speciesā€™ sensitivity are not necessarily congruent with measures of exposure. For instance, the range of all African species would be negatively affected by climate change, but their different sensitivity offers a more (Hydrictis maculicollis, Aonyx capensis) or less (Aonyx congicus) pessimistic perspective on their ability to cope with climate change. Also, highly sensitive species like the South-American Pteronura brasiliensis, Lontra provocax, and Lutra perspicillata might face no exposure to climate change. For the Asian Lutra sumatrana, climate change would instead lead to an increased, less fragmented, and more protected range extent, but the range extent would also be shifted into areas with higher human disturbances. Our study represents a balanced example of how to develop an index aimed at comparatively evaluating vulnerability to climate change of different species by combining different aspects of sensitivity and exposure, providing additional information on which to base more efficient conservation strategies

    Characterization of Newly Revealed Sequences in the Infectious Myonecrosis Virus Genome in \u3ci\u3eLitopenaeus vannamei\u3c/i\u3e

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    Infectious myonecrosis virus (IMNV) causes significant economic losses in farmed shrimp, where associated mortality in ponds can reach 70%. To explore host/pathogen interactions, a next-generation sequencing approach using lymphoid organ tissue from IMNV-infected Litopenaeus vannamei shrimp was conducted. Preliminary sequence assembly of just the virus showed that there were at least an additional 639 bp at the 5ā€² terminus and 23 nt at the 3ā€² terminus as compared with the original description of the IMNV genome (7561 nt). Northern blot and reverse transcription-PCR analysis confirmed the presence of novel sequence at both ends of the genome. Using 5ā€² RACE, an additional 4 nt were discovered; 3ā€² RACE confirmed the presence of 22 bp rather than 23 bp of sequence. Based on these data, the IMNV genome is 8226 bp in length. dsRNA was used to trigger RNA interference (RNAi) and suppress expression of the newly revealed genome sections at the 5ā€² end of the IMNV genome in IMNV-infected L. vannamei. An RNAi trigger targeting a 376 bp length of the 5ā€² UTR did not improve survival of infected shrimp. In contrast, an RNAi trigger targeting a 381 bp sequence in ORF1 improved survival to 82.2% as compared with 2.2% survival in positive control animals. These studies revealed the importance of the new genome sections to produce high-titre infection, and associated disease and mortality, in infected shrimp

    The Genetics of Dementia

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    Characterization of Newly Revealed Sequences in the Infectious Myonecrosis Virus Genome in \u3ci\u3eLitopenaeus vannamei\u3c/i\u3e

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    Infectious myonecrosis virus (IMNV) causes significant economic losses in farmed shrimp, where associated mortality in ponds can reach 70%. To explore host/pathogen interactions, a next-generation sequencing approach using lymphoid organ tissue from IMNV-infected Litopenaeus vannamei shrimp was conducted. Preliminary sequence assembly of just the virus showed that there were at least an additional 639 bp at the 5ā€² terminus and 23 nt at the 3ā€² terminus as compared with the original description of the IMNV genome (7561 nt). Northern blot and reverse transcription-PCR analysis confirmed the presence of novel sequence at both ends of the genome. Using 5ā€² RACE, an additional 4 nt were discovered; 3ā€² RACE confirmed the presence of 22 bp rather than 23 bp of sequence. Based on these data, the IMNV genome is 8226 bp in length. dsRNA was used to trigger RNA interference (RNAi) and suppress expression of the newly revealed genome sections at the 5ā€² end of the IMNV genome in IMNV-infected L. vannamei. An RNAi trigger targeting a 376 bp length of the 5ā€² UTR did not improve survival of infected shrimp. In contrast, an RNAi trigger targeting a 381 bp sequence in ORF1 improved survival to 82.2% as compared with 2.2% survival in positive control animals. These studies revealed the importance of the new genome sections to produce high-titre infection, and associated disease and mortality, in infected shrimp
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